ea0041gp185 | Reproduction & Endocrine Disruption | ECE2016
Schumacher Anne
, Sporke Dominique
, Ehrentraut Stefanie
, Claudia Zenclussen Ana
Introduction: Human Chorionic Gonadotropin (hCG) contributes to fetal tolerance by regulating innate and adaptive immune responses during pregnancy. Our previous results suggested a pregnancy protective effect of hCG through enhancement of regulatory T (Treg) cells and inhibition of dendritic cell (DC) maturation. Here, we aimed to investigate whether hCG contributes to Treg generation by modulating DC phenotype in vitro and in vivo in a murine model.<p c...